Treating allergic rhinitis by sublingual immunotherapy: a review
نویسندگان
چکیده
منابع مشابه
Treating allergic rhinitis by sublingual immunotherapy: a review.
OBJECTIVE Allergic rhinitis (AR) is a disease with high and increasing prevalence. The management of AR includes allergen avoidance, anti-allergic drugs, and allergen specific immunotherapy (AIT), but only the latter works on the causes of allergy and, due to its mechanisms of action, modifies the natural history of the disease. Sublingual immunotherapy (SLIT) was proposed in the 1990s as an op...
متن کاملSublingual immunotherapy in allergic rhinitis
Current treatment options for allergic rhinitis (AR) include allergen avoidance and environmental control, pharmacotherapy, nasal surgery and immunotherapy. Among these, immunotherapy is the only therapeutic option that modifies fundamental immunologic mechanism by inducing desensitization. Specific allergen immunotherapy has been used for 1 century since 1911 and subcutaneous immunotherapy (SC...
متن کاملSublingual immunotherapy for allergic rhinitis and conjunctivitis.
Sublingual immunotherapy (SLIT) for allergic respiratory diseases was first described in 1986 and immediately appeared as a viable alternative to the traditional subcutaneous route. Since then, more than 60 randomized controlled trials have been published, almost all with very favorable results. The average improvement over placebo in symptom score and medication use was always greater than 20%...
متن کاملSublingual Immunotherapy in Children with Allergic Rhinitis
The prevalence of allergic disease has been increasing over time and now represents a global health problem. For example, allergic disease in the UK affects up to 40% of children with allergic rhinitis accounting for a significant component of the allergic burden. There is also specific evidence for increasing prevalence of allergic rhinitis in the UK paediatric population, particularly among y...
متن کاملSublingual immunotherapy for pediatric allergic rhinitis: The clinical evidence.
Allergic rhinitis is estimated to affect 10%-20% of pediatric population and it is caused by the IgE-sensitization to environmental allergens, most importantly grass pollens and house dust mites. Allergic rhinitis can influence patient's daily activity severely and may precede the development of asthma, especially if it is not diagnosed and treated correctly. In addition to subcutaneous immunot...
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ژورنال
عنوان ژورنال: Annali dell'Istituto Superiore di Sanità
سال: 2012
ISSN: 0021-2571
DOI: 10.4415/ann_12_02_10